The cultivation of Black poplar mushroom (Agrocybe aegerita) began with the Romans and Greeks during the ancient ages, and are massively grown and sold in Asia and Australia nowadays because of its exceptional value in traditional medicine.  the black poplar mushroom carries a varieties of bioactive metabolites which could assist in the body’s free radical scavenger (1) and antifungal activities (2).

Active Constituents:

The black poplar mushroom contains a valuable source of beta-D-glucan, immuno-modulatory peptides, and agrocybin, which are responsible for restoring a healthy immune response (3) and supporting cytokine and interleukin production (4).

Pharmacological and Clinical Research: Original Research on Black poplar mushroom


1. Hifrichter et al., Pyridine as novel substrate for regioselective oxygenation with aromatic peroxygenase from Agrocybe aegerita.FEBS Lett. 2008 Dec 10;582(29):4100-6.
2. Ng et al., Agrocybin, an antifungal peptide from the edible mushroom Agrocybe cylindracea., Peptides. 2005 Feb;26(2):191-6.
3. Eum et al., Agrocybe chaxingu polysaccharide prevent inflammation through the inhibition of COX-2 and NO production., BMB Rep. 2009 Dec 31;42(12):794-9.
4. Chang et al., The antiproliferative and differentiating effects of human leukemic U937 cells are mediated by cytokines from activated mononuclear cells by dietary mushrooms., J Agric Food Chem. 2005 Jan 26;53(2):300-5.